This evaluation centers on the impact of the National Breast Cancer Coalition’s (NBCC) research and advocacy programs and efforts, with an emphasis on NBCC’s work after NBCC announced the Breast Cancer Deadline 2020 in 2010. I used documents, meeting minutes and agendas, press releases, scholarly literature, and interviews with NBCC leadership and affiliated researchers to examine the impact NBCC has made in lives and in the larger breast cancer research and advocacy ecosystem.