The University of Texas MD Anderson Cancer Center, the city of Houston, and the world of oncology have lost a great leader in Dr. John Mendelsohn, who contributed greatly to his institution, his community, and his field of expertise.
He was a pioneer in the development of anti-receptor antibodies to control tumor growth. He was the first to produce an antibody against the EGF receptor and demonstrate its anti-tumor activity in model systems. This served as a template for the subsequent development of antibodies against a host of growth factor receptors, and many of these are now used to treat a variety of cancers.
Not only was John an accomplished scientist, he was a compassionate and caring physician. These attributes, made him a great role model for physician-scientists. During his tenure, the stature of MD Anderson soared in the area of translational research.