Dan Sargent, one of the world’s foremost experts in oncology clinical trials, died unexpectedly on Sept. 22, 2016. Sargent died from an acute illness, Mayo officials said. He was 46.

“This is a tremendous loss to Mayo Clinic as well as the national and international cancer research community. Dan has given so much to so many,” said Robert Diasio, director of the Mayo Clinic Cancer Center. “We are deeply saddened by his passing. Our thoughts and prayers are with his wife and family.”

Sargent joined Mayo Clinic Rochester after earning his PhD in biostatistics from the University of Minnesota in 1996. At the time of his death, he was the Ralph S. and Beverley E. Caulkins Professor of Cancer Research, and the Chair of the Division of Biomedical Statistics and Informatics in the Department of Health Sciences Research at the Mayo Clinic.